Current methods of treatment gingivostomatitis in cats, with insight into mesenchymal stem cell therapy

Gingivostomatitis is a common finding in veterinary feline patients. Many conditions and infectious agents have been suggested to play part pathogenesis of chronic gingivostomatitis (FCGS), including pathogens noninfectious factors. The most approaches treating are pharmacotherapy surgical dental extraction. However, despite the application these methods, treatment progress often unsatisfactory: many cats show little or no improvement require further treatment. Data from literature indicate high therapeutic efficacy tooth extraction combined with mesenchymal stem cell application. This method can significantly improve effectiveness patient’s prognosis compared alone, which choice case gingivostomatitis. Mesenchymal cells multipotent progenitor that divide, differentiate, eventually trigger genesis different tissues. Furthermore, they exhibit anti-inflammatory, anti-apoptotic, antimicrobial effects modulate neoangiogenesis. These other properties cells, whose biology has studied described detail, explain their beneficial FCGS For surgeons considering this method, sources include bone marrow adipose tissue. There established isolation protocols, summarized publication.